This report reviews the study of open heavy-flavour and quarkonium production in high-energy hadronic collisions, as tools to investigate fundamental aspects of Quantum Chromodynamics, from the proton and nucleus structure at high energy to deconfinement and the properties of the QuarkâGluon Plasma. Emphasis is given to the lessons learnt from LHC RunÂ 1 results, which are reviewed in a global picture with the results from SPS and RHIC at lower energies, as well as to the questions to be addressed in the future. The report covers heavy flavour and quarkonium production in protonâproton, protonânucleus and nucleusânucleus collisions. This includes discussion of the effects of hot and cold strongly interacting matter, quarkonium photoproduction in nucleusânucleus collisions and perspectives on the study of heavy flavour and quarkonium with upgrades of existing experiments and new experiments. The report results from the activity of the SaporeGravis network of the I3 Hadron Physics programme of the European Union 7 th Framework Programme.

Germany

France

Italy

CERN

Czechia

Serbia

Spain

Japan

China

South Africa

Russia

Chile

Netherlands

United States

Norway

India

Heavy-flavour and quarkonium production in the LHC era: from proton–proton to heavy-ion collisions