We construct Seiberg-like dualities of 3D <math><mi>N</mi><mo>=</mo><mn>2</mn></math> general quiver gauge theories with unitary, symplectic, and orthogonal gauge groups coupled to fundamental and bifundamental matter fields. We illustrate this with several examples of linear, circular, and star-shaped quiver gauge theories. We examine the local operators in the theories by computing supersymmetric indices and also find precise matching for the proposed dualities as strong evidence. We also generalize the dualities in the presence of a boundary on which the theories obey <math><mi>N</mi><mo>=</mo><mo>(</mo><mn>0</mn><mo>,</mo><mn>2</mn><mo>)</mo></math> chiral half-BPS boundary conditions and check the matching of half-indices.