The leading-order chiral Lagrangian for the baryon octet and decuplet states coupled to Goldstone bosons and external sources contains six low-energy constants. Five of them are fairly well-known from phenomenology, but the sixth one is practically unknown. This coupling constant provides the strength of the (p-wave) coupling of Goldstone bosons to decuplet states. Its size and even sign are under debate. Quark models and quantum chromodynamics (QCD) for a large number of colors provide predictions, but some recent phenomenological analyses even suggest an opposite sign for the Delta-pion coupling. The Goldberger-Treiman relation connects this coupling constant to the axial charge of the Delta baryon. This suggests a Wu-type experiment to determine the unknown low-energy constant. While this is not feasible in the Delta sector because of the large hadronic width of the Delta, there is a flavor symmetry related process that is accessible; the weak semileptonic decay of the Omega baryon to a spin $3/2$ cascade baryon. A broad research program is suggested that can pin down at least the rough size and the sign of the last unknown low-energy constant of the leading-order Lagrangian. It encompasses experimental measurements, in particular the forward-backward asymmetry of the semileptonic decay, together with a determination of the quark-mass dependences using lattice QCD for the narrow decuplet states and chiral perturbation theory to extrapolate to the Delta sector. Besides discussing the strategy of the research program, the present work provides a feasibility check based on a simple leading-order calculation.